Breast

September 23, 2021 by 1 Comment

Welcome to your Breast

52 y/o woman with breast massIs it benign or malignant?

How would you grade this tumor?
How would you subtype this tumor?
If Her-2 by IHC is equivocal whats your next best step?

One Reply to “Breast”

  1. pathfiles says:
    September 28, 2021 at 4:36 pm

    This is a malignant tumor. It is invasive ductal carcinoma/ tubular carcinoma. This tumor is Grade by by Nottingham grading system. Grade 1 tumors are mostly Luminal A type. Please take a look at the Molecular subtypes of Breast Carcinoma https://pathfiles.com/index.php/2020/08/19/molecular-subtypes-of-breast-cancer/ . If by IHC Her-2 neu is equivocal, Her-2 amplification study would be the next best step.

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