One Reply to “Appendix”

1. pathfiles says:

   September 23, 2021 at 2:34 am

   This is an appendiceal adenocarcinoma in contrast to LAMN. LAMN usually shows pushing margins. On the contrary adenocarcinoma has invasive margins. Adenocarcinomas of the appendix can occur anywhere in the appendix. Appendiceal adenocarcinomas harbor KRAS mutations predominantly. 30-70% have GNAS mutations. BRAF and MSI are rare in appendiceal mucinous adenocarcinomas. Non mucinous adenocarcinomas however, can harbor more MSI mutations.

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