Granular Cell Tumor

September 12, 2020 by No Comments

Granular cell tumors are usually benign. Malignant and benign granular cell tumors can be differentiated on clinical presentation and histomorphologic characteristics are confirmed using Fanburg-Smith criteria. Fanburg-Smith criteria consists of the following features: nuclear spindling, necrosis, increased mitosis (>2/10hpf), vesicular nuclei/ large nucleoli, increased N/c ratio and pleomorphic nuclei. For benign and atypical tumors wide local excision is curative; however for malignant lesions adjuvant radiotherapy results in a good outcome.







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