Granular Cell Tumor
Granular cell tumors are usually benign. Malignant and benign granular cell tumors can be differentiated on clinical presentation and histomorphologic characteristics are confirmed using Fanburg-Smith criteria. Fanburg-Smith criteria consists of the following features: nuclear spindling, necrosis, increased mitosis (>2/10hpf), vesicular nuclei/ large nucleoli, increased N/c ratio and pleomorphic nuclei. For benign and atypical tumors wide local excision is curative; however for malignant lesions adjuvant radiotherapy results in a good outcome.