Molecular subtypes of Breast Cancer

There are five main subtypes of breast cancer that includes: luminal A, luminal B, Her 2 enriched, basal like and normal like. The normal like subtype is similar to Luminal A (ER ,PR (+), Her2 (-)) and even though its prognosis is good it is worse than luminal A subtype. Since it is similar to luminal A it is not depicted in the picture. The Her 2 enriched though have a worse prognosis is treated successfully with treatments aimed at Her2 protein like tratuzumab. The triple negatives are common in younger and African American women for unknown reasons. Research suggests arise from luminal progenitor cells and not myoepithelial cells.

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